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Phentermine: Usage, dosage, side effects, alternatives-

Phentermine has been known as a popular weight-loss drug since the late 1950s. However, its effectiveness comes with some risks. If you’re considering using Phentermine as part of your weight-loss program, it’s important to understand both the potential benefits and possible side effects. In this regard, let’s explore Phentermine, understand its working mechanism, and discuss usage, dosage, side effects, and alternatives. We’ll also provide important safety information about taking Phentermine. Read on to learn if it’s right for you.

What is Phentermine?

Phentermine is an ideal medication for short-term weight loss. Doctors may prescribe to overweight or obese people who find it difficult to lose weight through diet and exercise.
Doctors prescribe it for adults with:

  • BMI of 30 or above
  • BMI of 27 or above with high blood pressure/type 2 diabetes/high cholesterol

The drug curbs your appetite by stimulating the release of norepinephrine, a neurotransmitter that helps to regulate hunger. You can buy Phentermine online in both oral and injectable form.

How soon does Phentermine start to work?

It does not start working immediately, and there could be several reasons for it. For instance, anticholinergic drugs, blood thinners, and seizure medications can slow down the effects of Phentermine. The same goes for MAO inhibitors as well. That said, the drug alone can not help you lose weight faster unless you add other modalities into your lifestyle, including- a healthy diet, regular exercise, lowering calories, etc.

Phentermine dosage-

The recommended phentermine dosage for these individuals is 15-37.5 mg per day. However, before you buy Phentermine online, let your doctor suggest the ideal dosage for your condition.

You should take this drug on an empty stomach, one hour before breakfast or two hours after breakfast. Though you can take it with or without food, taking it with food may decrease its absorption and reduce its effectiveness.

But remember, if you miss a dose of Phentermine, do not overdose on it next time, as this may cause insomnia.

Phentermine side effects-

Common side effects of Phentermine include:

  • Headache
  • Dizziness
  • Insomnia
  • Dry mouth
  • Constipation
  • Blood pressure

In the event of such side effects, you should consult with your doctor immediately.

Pregnant or breastfeeding women should also avoid taking Phentermine. Additionally, if you have any medical conditions such as heart disease, high blood pressure, or diabetes, make sure Phentermine will not cause any unwanted drug interactions with your existing medication.

Phentermine alternatives-

Though Phentermine can help people lose weight, it is not suitable for everyone and can have side effects.

There are several alternative medications to Phentermine that can be used for weight loss. These include:

Orlistat: Orlistat is a medication that inhibits the absorption of fat from the diet. It is available as a prescription (Xenical) and over-the-counter (Alli).

Liraglutide: Liraglutide is a medication that increases satiety and decreases hunger. It is available by prescription only (Saxenda).

Bupropion/naltrexone: Bupropion/naltrexone is a combination medication that helps reduce appetite and promote weight loss. It is available by prescription only (Contrave).

Phendimetrazine: Phendimetrazine is a stimulant medication that suppresses appetite. It is available by prescription only.

Phentermine and Alcohol-

Consuming alcohol while taking Phentermine can be dangerous because it can increase drowsiness caused by the medication. This can reduce your ability to drive or operate machinery. Additionally, Phentermine may interact with Anticholinergic drugs, blood thinners, seizure medications, and MAO inhibitors which can further increase drowsiness as well as cause difficulty breathing. Therefore, it is best to consult your doctor before combining Phentermine with any alcoholic beverages.

Can Phentermine make you feel tired?

It depends on the patient and their lifestyle. While Phentermine is predominantly helpful for weight loss, it may also cause fatigue as a side effect due to its anticholinergic drugs.

Anticholinergic drugs can block the action of acetylcholine in the brain and body, leading to drowsiness and lethargy. In addition, taking medications like blood thinners, seizure medications, and MAO inhibitors along with Phentermine can also cause the same. However, your doctor may prescribe any additional medication alongside Phentermine to avoid fatigue with ease.


Though Phentermine is highly useful for fighting obesity, taking it in combination with lifestyle changes can offer you maximum effectiveness. Although it has been found to be safe and effective, there are some potential side effects.

Additionally, there are several alternative treatments available for those looking to lose weight without using such medications. Therefore, we recommend talking to your doctor before starting Phentermine for weight loss.


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